Patented RDC-EV Technology 99.9% Pure
The Future of Regenerative Aesthetic Homecare

The Platinum Standard. Regeneration, Reimagined.

Clinically advanced daily homecare, powered by patented RDC-EV Rosa Damascena Callus Extracellular Vesicle technology. Dispensed exclusively through a network of elite aesthetic providers.

The Science of the Rose

The most validated EV science in the world.

From the world's leader in extracellular vesicles for safety, consistency and performance comes ASCEplus PLATINUM: the Platinum Standard in professionally dispensed, clinically directed daily homecare.

99.9%

Purity

Purified through patented EXO-SCRT™ technology. Not an extract. Not a hydrosol. Not an oil.

78+

Global Patents

Including the world's first patented Rosa Damascena callus EV platform.

61+

Publications

Peer-reviewed research validating ExoCoBio's extracellular vesicle technology.

2.3M+

Clinical Cases

Documented across more than 70 countries with the in-clinic Exosome Regenerative Complex™ line.

The Science of the Rose →
The Clinical Homecare Extension

The appointment is one moment. The result lives every day after.

ASCEplus PLATINUM is what happens next. Dispensed by the provider and directed by the provider, it carries the science of the treatment room into the patient's morning and evening ritual, so every appointment is extended, not just remembered.

The Biosignal Collection · The Advanced Treatment

The signal, amplified.

Firmness, fine lines, fatigue and recovery after in-clinic treatment.

The Luminous Collection · The Glow Ritual

The signal, illuminated.

Clarity, even tone and radiance, morning and evening.

From the Providers

"They built the science first, then the product. That is the right order."

TJ TsayMD · Aesthetic Physician

"What drew me to ASCEplus PLATINUM™ was not hype, but the science behind it. I value technologies that focus on cellular communication, purification, and true regenerative potential."

Shino Bay AguileraDO, FAOCD · Shino Bay Cosmetic Dermatology & Laser Institute

"The science behind Exosome by BENEV is unlike anything I have seen in regenerative aesthetics. The idea of extending that same pharmaceutical grade exosome science into a homecare protocol is exactly what this industry has been missing."

Gretchen FrielingMD · GFACE MD

"ASCEplus PLATINUM™ is the clearest expression of it yet — setting The Platinum Standard in Regenerative Aesthetics not just in the clinic, but in the hands of every patient who takes it home."

JD McCoyNMD · Contour Medical

Be among the first
to experience the difference.

The Foundation

Two Companies that Created the Category

Two Leaders, One Vision: Redefining Global Aesthetics

The partnership between ExoCoBio and BENEV represents a powerful synergy of science, innovation, and market leadership, shaping the future of regenerative aesthetics by combining cutting-edge exosome technology with a relentless commitment to quality and results.

Before exosomes were a trend, ExoCoBio and BENEV made them a standard. Their in-clinic Exosome Regenerative Complex™ and Exosome Regenerative Complex+™ brought pharmaceutical-grade manufacturing discipline to cosmetic exosomes for the first time, purified to 99.9%, documented across more than 2.3 million clinical cases in over 70 countries.

ASCEplus PLATINUM is the next chapter: the same science, carried beyond the treatment room and into every day that follows.

ExoCoBio · The Science
  • The world's largest exosome biotech company
  • 78+ global patents
  • Over $80M invested in R&D and manufacturing since 2017
  • A $41M ExoGMP™ facility, certified by the Korean MFDS and to ISO standards
  • 61+ peer-reviewed publications
  • 7 AMWC Monaco Awards
  • Extracellular vesicle science validated across human, plant and other biological sources, and the world's first patented Rosa Damascena callus EV platform
BENEV · The Clinic
  • Exclusive U.S. commercialization partner
  • FDA-registered cosmetic manufacturer
  • 26+ years bringing Korean aesthetic technology to the U.S.
  • 25,000+ clinic relationships worldwide, including 4,000+ in the U.S.
  • Guided by a Medical Advisory Board and 80+ U.S. key opinion leaders

United in 2023 to set The Platinum Standard in Regenerative Aesthetics: one partnership controlling every step, from research and purification to manufacturing and the clinic.

"They built the science first, then the product. That is the right order."
TJ Tsay, MDAesthetic Physician

See the science
behind the partnership.

ASCEplus PLATINUM

The Science of the Rose.

From the world's leader in extracellular vesicles for safety, consistency, and performance comes ASCEplus PLATINUM.

The PLATINUM STANDARD in professionally dispensed, clinically directed daily homecare, powered by award-winning, patented RDC-EV (Rosa Damascena Callus Extracellular Vesicle) technology.

This is next-generation aesthetics, built on the most validated EV science in the world.

99.9%

Purity

Purified through patented EXO-SCRT™ technology. Not an extract. Not a hydrosol. Not an oil.

78+

Global Patents

Including the world's first patented Rosa Damascena callus EV platform.

61+

Publications

Peer-reviewed research validating ExoCoBio's extracellular vesicle technology.

2.3M+

Clinical Cases

Documented across more than 70 countries with the in-clinic Exosome Regenerative Complex™ line.

The Damask Rose

Taken where it has never been: to the cell.

For more than a thousand years, the Damask rose has been the most treasured flower in beauty. It is also one of the most studied botanicals in dermatological science, rich in flavonoids, polyphenols and terpenoids, with decades of published research behind it.

ASCEplus PLATINUM takes the rose where it has never been: to the cell. When a rose is wounded, it forms a callus, a cluster of young, undifferentiated cells that gathers to repair the plant. ExoCoBio cultivates this callus under controlled laboratory conditions, then isolates its extracellular vesicles: the nano-sized messengers cells use to communicate, each carrying proteins, lipids and RNA.

Purified to 99.9% through patented EXO-SCRT™ technology, they become RDC-EV. Not an extract. Not a hydrosol. Not an oil. The rose's own signal.

Patented Platform

Nature's Rarest Signal.

The source changes. The science does not. RDC-EV is made with the same EXO-SCRT™ technology, the same purity standard and the same manufacturing discipline behind ExoCoBio and BENEV's in-clinic exosome line. Only the source is new.

I

Purified, not processed.

EXO-SCRT™ begins with four master cell banks and uses tangential flow filtration to remove cellular debris, lipoproteins and non-vesicular material, under rigorous QC/QA at every batch. What remains is the vesicle, and its complete message, intact.

II

Grown, not harvested.

The callus is cultivated rather than picked from the field: no seasons, no soil, no variation from crop to crop. Every bottle begins from the same source.

III

Stable from manufacture to the moment of use.

After EXO-SCRT™ purification, the vesicles are held in a stabilized formulation that distributes their efficacy evenly with every application. In the Renewal Glazing Mist, RDC-EV is lyophilized, a process that keeps the vesicles' lipid bilayer membrane intact and stable for two to three years, and sealed inside the Exocapsule® until the patient activates it.

IV

Published.

Rose callus extracellular vesicles have been biologically characterized and evaluated in a dermatological case series.1 2

The Platinum Standard

Rests on three promises.

Promise One

Safety.

Plant-derived vesicles, purified to 99.9%, skin-irritation tested and made in cGMP, ISO-certified facilities.

Promise Two

Consistency.

The same vesicle quality and stability in every bottle, every batch, every application.

Promise Three

Performance.

Clinically studied formulas, dispensed and directed by a provider.

For the Provider

EXO-SCRT™: The Technology That Makes the Difference

EXO-SCRT™ stands for exosome stem cell regenerative technology. It is ExoCoBio's proprietary separation, refinement and concentration process: a multi-stage purification that removes cellular debris, lipoproteins, uncharacterized proteins and non-vesicular material, leaving 99.9% pure extracellular vesicles carrying a concentrated payload of growth factors, bioactive lipids, proteins, messenger RNA and microRNA.

This same process (the same technology, the same purity standard, the same manufacturing discipline) is applied to Rosa Damascena callus cells to create RDC-EV, Rosa Damascena Callus Extracellular Vesicles.

The source changes. The science does not.

"EXO-SCRT™ is the purification standard that separates real exosome science from marketing noise. When I explain to patients what ExoCoBio has built — 99% pure extracellular vesicles, pharmaceutical-grade manufacturing, 60+ publications — they understand immediately why Exosome by BENEV is in a class of its own. ASCEplus PLATINUM™ carries that authority directly into their daily routine."
Gideon Kwok, DOSkin Perfect
For the Provider

The Problem with 'Plant Exosomes' and Why RDC-EV Is Categorically Different

The botanical exosome space has grown quickly, and with that growth has come significant confusion. Products marketed as 'plant exosomes' or 'botanical stem cell extracts' range enormously in what they actually contain, how they are manufactured, and whether they deliver measurable extracellular vesicle science at all.

The critical distinction providers must understand is this: most plant-derived "exosome" products are not exosomes. They are plant extracts (conditioned media, whole-cell lysates, hydrosols, oils, or unfractionated botanical materials) marketed under the exosome umbrella because the term carries commercial appeal. These products may contain bioactive compounds. They do not contain 99.9% pure extracellular vesicles. They have not been through a pharmaceutical-grade purification process. They do not carry the concentrated, targeted biological signaling that true extracellular vesicle science delivers.

RDC-EV is fundamentally different
  • Not a plant extract.
  • Not a hydrosol.
  • Not an oil.
  • Not conditioned media.

It is extracellular vesicle science, applied to a botanical callus (stem cell) source for the first time, using the same EXO-SCRT™ technology that makes the Exosome by BENEV human adipose stromal cell line the global standard in the category.

For the Provider

Why Rosa Damascena

Rosa Damascena has one of the most extensively studied profiles of any botanical in dermatological science. Its biological compounds include flavonoids, polyphenols, terpenoids and lipid-based signaling molecules with well-characterized anti-inflammatory, antioxidant and skin-conditioning properties, documented across decades of published research.

When purified to 99.9% through EXO-SCRT™, these Rosa Damascena callus extracellular vesicles become something no botanical extract has ever been: a shelf-stable homecare line built on pharmaceutical-grade extracellular vesicles, delivering targeted regenerative signaling from a botanically sourced, clinically credible platform.

For the Provider

The Published Science

Study 1 · Preprint1

First Biological Characterization of Rose Stem Cell Extracellular Vesicles

This is the first study to show the presence of viable and stable rose stem cell extracellular vesicles in rose stem cell cultures. Together, the data suggest that these are membrane enclosed extracellular vesicles, including the presence of membrane-associated proteins and protein functions, as well as characterized RNA.

bioRxiv preprint, 2023 · not yet peer-reviewed

Study 2 · Clinical Case Series2

Rose Stem Cell Extracellular Vesicles Across Dermatological Applications

Rose stem cell extracellular vesicles show potential as a valuable treatment in dermatology, as evidenced by the positive results across multiple skin conditions and their alignment with existing literature on plant-derived exosomes.

J Cosmet Dermatol, 2025

"What drew me to ASCEplus PLATINUM™ was not hype, but the science behind it. As someone deeply passionate about Bioregenerative and Orthomolecular Science, I value technologies that focus on cellular communication, purification, and true regenerative potential. What ExoCoBio and BENEV have created reflects the exciting direction aesthetic medicine is evolving toward... more precision, more biological intelligence, and a deeper respect for cellular health. I am proud to bring this technology to my patients as part of my commitment to cell conscious regenerative aesthetics."
Shino Bay Aguilera, DO, FAOCDShino Bay Cosmetic Dermatology & Laser Institute
  1. Won YJ, Lee E, Min SY, Cho BS. Biological function of exosome-like particles isolated from rose (Rosa damascena) stem cell culture supernatant. bioRxiv preprint, 2023. doi:10.1101/2023.10.17.562840
  2. Majewska L, Dorosz K, Kijowski J. Efficacy of rose stem cell-derived exosomes (RSCEs) in skin treatment: from healing to hyperpigmentation management: case series and review. J Cosmet Dermatol. 2025;24(1):e16776. doi:10.1111/jocd.16776

See the signal at work,
formula by formula.

The Collections

One Signal. Two Expressions.

Every ASCEplus PLATINUM formula begins with RDC-EV, each at its own precisely dosed concentration, calibrated to the work it is designed to do. What surrounds that signal decides what it does.

One collection is the advanced treatment. The other is the daily glow ritual. Together, they carry the rose signal from the treatment room into every day.

The Biosignal Collection · The Advanced Treatment

The signal, amplified.

Every Biosignal formula is built to carry RDC-EV at the line's highest concentrations. The dose is the first amplifier. Then eachEach Biosignal formula strengthens the rose's message in its own way, toward firmness, smoothness and recovery after in-clinic treatment.

  • Renewal Glazing Mist. RDC-EV lyophilized in its own Exocapsule®, released into sixteen peptides and the cellular coenzymes NAD⁺ and Coenzyme A: messengers the skin itself uses.
  • Biosignal Revitalizing Concentrate. The most concentrated expression of the signal: RDC-EV in a pure rose-water base, with adenosine, niacinamide and vitamin B12.
  • Intensive Eye Concentrate. RDC-EV with five signal peptides, Sodium DNA and caffeine, for the orbital contour.
The Luminous Collection · The Glow Ritual

The signal, illuminated.

In every Luminous formula, RDC-EV is joined by tone-perfecting actives: niacinamide, glutathione, and tranexamic acid or arbutin. The three treatment formulas add vitamin C and light-reflecting minerals, so skin looks more even over time and luminous the moment they are applied. PhotoDefense completes the ritual with SPF 50+ PA++++ protection. Tranexamic acid and arbutin appear only in this collection.

Biosignal amplifies the signal. Luminous turns it into glow. Together, they are the Platinum Ritual.

Precisely Dosed · RDC-EV by Formula

Dosed for purpose.

Biosignal · The Advanced TreatmentRDC-EVLuminous · The Glow RitualRDC-EV
Renewal Glazing MistTBA ppmRefining Toning EssenceTBA ppm
Biosignal Revitalizing ConcentrateTBA ppmLuminous Perfecting SerumTBA ppm
Intensive Eye ConcentrateTBA ppmRadiance Corrective CreamTBA ppm
PhotoDefense SPF 50+ PA++++TBA ppm
The Proof, by the Label

Two collections. Side by side.

Biosignal · The Advanced TreatmentLuminous · The Glow Ritual
PurposeFirmness, fine lines, fatigue, recovery after treatmentClarity, even tone, radiance
In every formulaRDC-EV at the line's highest concentrationsRDC-EV + niacinamide + glutathione + tranexamic acid or arbutin
Only in this collectionPeptides · NAD⁺ · Coenzyme A · Sodium DNA · the Exocapsule®Tranexamic acid · arbutin · light-reflecting minerals · five-ceramide complex · UV filters
Peptides16 in the Mist · 6 in the EyeNone
Tone-perfecting actives1 to 3 per formula4 per treatment formula · 3 in PhotoDefense
Sun protectionNonePhotoDefense SPF 50+ PA++++

Counts taken from each product's ingredient list. Tone-perfecting actives counted: niacinamide, glutathione, tranexamic acid, arbutin and vitamin C.

The Platinum Ritual

Eight steps. Two collections.

  1. Cleanse

  2. Refining Toning Essence · Luminous

  3. Renewal Glazing Mist · Biosignal

  4. Biosignal Revitalizing Concentrate · Biosignal

  5. Luminous Perfecting Serum · Luminous

  6. Intensive Eye Concentrate · Biosignal

  7. Radiance Corrective Cream · Luminous

  8. A broad-spectrum sunscreen, every morning

Be among the first
to experience the difference.

The Collection

One signal. Two expressions.

Every ASCEplus PLATINUM formula is powered by patented RDC-EV technology, purified to 99.9%. The Biosignal Collection is the advanced treatment; the Luminous Collection is the daily glow ritual.

PhotoDefense SPF 50+ PA++++ is available in select international markets and is not sold in the U.S.

Be among the first
to experience the difference.

The Clinical Homecare Extension

The Appointment Is One Moment. The Result Lives Every Day After.

A patient leaves the clinic looking their best. The weeks that follow decide whether that result compounds or fades.

ASCEplus PLATINUM is what happens next. Dispensed by the provider and directed by the provider, it carries the science of the treatment room into the patient's morning and evening ritual, so every appointment is extended, not just remembered.

In the clinicAt home
Exosome Regenerative Complex™ and Exosome Regenerative Complex+™, applied after in-clinic proceduresASCEplus PLATINUM, the daily extension, powered by RDC-EV
Provider-performedProvider-dispensed, provider-directed
One appointmentEvery morning, every evening, between every visit
"ASCEplus PLATINUM™ is the clearest expression of it yet — setting The Platinum Standard in Regenerative Aesthetics not just in the clinic, but in the hands of every patient who takes it home."
JD McCoy, NMDContour Medical
Integrating ASCEplus PLATINUM™

The Ritual That Goes Home With Your Patient

For providers already using Exosome by BENEV professional products, ASCEplus PLATINUM™ is the missing piece: the premium homecare ritual that transforms a single appointment into an ongoing result.

Your patient leaves the clinic looking luminous. ERC and ERC+ support the appearance of skin that looks visibly calmer, more radiant and refined in the critical hours after treatment. ASCEplus PLATINUM™ is what happens next: seven formulas powered by patented RDC-EV, Rosa Damascena Callus Extracellular Vesicle science, designed to sustain and extend that visible result through every step of your patient's daily routine.

The result compounds. Appointments feel more valuable. Patients come back more loyal. And the practice captures retail revenue from a homecare line backed by science they already trust.

"What sets Exosome by BENEV apart is simple: it is real exosome science. Not a plant extract dressed up with marketing language — actual, purified, validated extracellular vesicles at 99% purity. I use these solutions in my practice because my patients deserve that standard of precision. ASCEplus PLATINUM™ brings that science home, and that is something I am proud to celebrate and recommend without hesitation."
Jessica Manges, ARNPLux Injectables
The Market Moment

The right science, at the right moment.

Clinical K-Beauty Is the Fastest-Growing Consumer Segment

Consumers are increasingly seeking science-backed, results-driven products for use between clinical appointments. The clinical K-Beauty segment (Korean-developed skincare anchored in published science, pharmaceutical manufacturing and demonstrable active ingredient delivery) is growing faster than any other category in the premium skincare market. ASCEplus PLATINUM™ occupies this space with scientific authority: 61+ publications, 99.9% purity, cGMP manufacturing, and the ExoCoBio EXO-SCRT™ platform behind every product.

First-Mover Advantage

Exosome technology leads.

Consumer awareness of exosomes as a meaningful skincare technology is growing rapidly (search interest has surged more than 550% year-over-year). Patients are arriving at consultations having researched exosomes and asking their providers specifically about them. Most of what they find does not meet the scientific standard that ExoCoBio has set. ASCEplus PLATINUM™, powered by patented RDC-EV technology, is a homecare line that can answer this patient demand with pharmaceutical-grade extracellular vesicle science behind it.

Patient Loyalty

Post-treatment homecare is where loyalty lives.

The clinical appointment is one moment in a patient relationship. The weeks between appointments are where the result either compounds or plateaus. Providers who give patients a scientifically credible homecare regimen (provider-recommended, patient-purchased) build a relationship that extends beyond the treatment room and drives retail revenue the practice controls. ASCEplus PLATINUM™ backs that model with 99.9% pure, pharmaceutical grade extracellular vesicle science.

Distribution Advantage

BENEV's existing network.

The commercial launch of ASCEplus PLATINUM™ is not starting from zero. BENEV's existing network of more than 4,000 active U.S. clinic relationships provides immediate access to a pre-qualified audience of providers who already understand and trust the ExoCoBio × BENEV science platform. These practices have seen the clinical results of the core Exosome by BENEV line. They have been waiting for this homecare line launch with a brand backed by science they trust.

"Patients today are highly educated about regenerative aesthetics and increasingly seek technologies supported by meaningful science rather than trends alone. What distinguishes ExoCoBio and BENEV apart from the rest of the market is their commitment to advancing clinically grounded exosome technology with a strong emphasis on formulation quality and scientific innovation. ASCEplus PLATINUM™ reflects the growing evolution of regenerative skincare and the integration of sophisticated, physician-guided homecare into modern aesthetic medicine."

Eunice ParkMD · Aire MD Aesthetics Spa & Plastic Surgery

"The science behind Exosome by BENEV is unlike anything I have seen in regenerative aesthetics. My patients look better, and come back more loyal because they love the results. The idea of extending that same pharmaceutical grade exosome science into a homecare protocol is exactly what this industry has been missing. ASCEplus PLATINUM™ is a game changer — full stop."

Gretchen FrielingMD · GFACE MD
For the Provider

What Providers Need to Know: Evaluating Extracellular Vesicle Products

As the exosome and extracellular vesicle category expands, the provider's responsibility to evaluate products rigorously becomes more important. The following framework provides a basis for that evaluation.

01

Manufacturing Standard

The most important question is not what a product claims to contain, but how it is manufactured. Reproducibility, batch-to-batch consistency and QC/QA standards are the hallmarks of credible extracellular vesicle science. ExoCoBio's cGMP-certified ExoGMP™ facility, with its $41 million manufacturing investment, provides this standard for every product in both the Exosome by BENEV and ASCEplus PLATINUM™ lines.

02

Purity Standard

True extracellular vesicle science requires isolation and purification of vesicles from the complex mixture of cellular secretions. Products that do not specify purity, or describe themselves as conditioned media, are not delivering 99.9% pure extracellular vesicles. EXO-SCRT™ technology, using four master cell banks, tangential flow filtration (TFF) and rigorous QC/QA, produces 99.9% pure extracellular vesicles from both the human adipose stromal cell source and the Rosa Damascena callus source of RDC-EV.

03

Evidence Base

Peer-reviewed publication in indexed journals is the accepted standard of evidence in clinical medicine. ExoCoBio holds 61+ peer-reviewed publications validating its extracellular vesicle technology. Providers should ask any exosome product supplier for their publication record and evaluate it accordingly.

04

Registration

In the U.S., exosome and extracellular vesicle products used as topical cosmetics must comply with applicable regulations, including the Modernization of Cosmetics Regulation Act (MoCRA). The core Exosome by BENEV line holds PCPC registration (2017-6058) and INCI recognition (Mono ID: 30965). ASCEplus PLATINUM™ is manufactured to the same standard.

"Sixty-plus peer-reviewed publications. Ninety-nine percent purity. INCI registration. These are not just numbers — they are proof of a commitment to doing the work that most brands skip entirely. I have used Exosome by BENEV professional solutions and seen the results firsthand. ASCEplus PLATINUM™ is a homecare line built on a foundation that the rest of the market simply cannot match. This is a milestone worth celebrating."

Lyris Verdura DominicConcierge HRS

"I have followed the exosome category closely for years. The difference between what ExoCoBio has built and what the rest of the market is selling is not incremental — it is categorical. Ninety-nine percent purity, 60+ peer-reviewed publications, cGMP manufacturing. When a homecare line carries that same standard, it becomes something I am genuinely proud to put in my patients' hands. ASCEplus PLATINUM™ is exactly that."

Saami KhalifianMD, FAAD · Soma Aesthetics
For Partner Practices

The Platinum Partnership

Practice Support · Education · In the Press · Gifts with Purchase

Every ASCEplus PLATINUM practice is supported from launch onward: the materials to tell the story, the education to tell it well, and the gifts to make every regimen feel like a ritual. Everything except the display and the catalog lives on ASCEplus PLATINUM University.

Practice Support

  • HCP Displayone per clinic, provided with the minimum opening order
  • HCP Catalog
  • HCP Pricing Sheeton ASCEplus PLATINUM University
  • Patient Brochureon ASCEplus PLATINUM University
  • Clinic Posteron ASCEplus PLATINUM University
  • Clinic Standing Banneron ASCEplus PLATINUM University
  • Clinic Tabletop Banneron ASCEplus PLATINUM University
  • Teaser Videoon ASCEplus PLATINUM University
  • Social Mediaon ASCEplus PLATINUM University
  • Product Photographyon ASCEplus PLATINUM University

Education

  • HCP Training PowerPointon ASCEplus PLATINUM University
  • Clinic On-Demand Webinar + Mini Quizfeaturing Dr. Suneel Chilukuri, Dr. TJ Tsay, Dr. Gideon Kwok, Lyris Verdura Dominic, Dana Herbertson, Jennifer Levine, Dr. Shino Bay Aguilera, Dr. Justin Harper, Dr. Tiphany Hall and more, on ASCEplus PLATINUM University
  • Mini Clinic Training Moduleseach with a quiz, on ASCEplus PLATINUM University
  • Monthly Webinar Scheduleon ASCEplus PLATINUM University

In the Press

  • Press Releaseon ASCEplus PLATINUM University
  • The Aesthetic Guideon ASCEplus PLATINUM University
  • People (coming soon)on ASCEplus PLATINUM University
  • Elle (coming soon)on ASCEplus PLATINUM University

Gifts with Purchase

  • Gift Bagwith ExoCoBio × BENEV branded tissue paper, included with the minimum order
  • Bling Shirtincluded with the minimum order, or available to purchase for $45
  • XXL Scrunchie (coming soon)included with the minimum order during select months
  • Headband (coming soon)included with the minimum order during select months
  • Scarf (coming soon)included with the minimum order during select months
  • Korean Makeup Fan (coming soon)included with the minimum order during select months
  • Handheld Mirror (coming soon)included with the minimum order during select months

Be Among the First. Experience the Difference.

A complete line of professionally dispensed, clinical daily homecare, powered by patented RDC-EV technology. Available exclusively through a network of elite aesthetic providers.

Full product details, clinical homecare rituals and pricing are available now for qualified practices. This is regenerative aesthetics at its most refined, where science meets the rarest ingredients in nature.

The Biosignal Collection · The Advanced Treatment

Renewal

Glazing Mist

An advanced dual-phase treatment mist

A dual-phase treatment mist powered by patented RDC-EV and engineered to do two things at once: instantly cushion the skin and visibly firm it over time. Purified through ExoCoBio's patented EXO-SCRT™ process, RDC-EV is lyophilized and sealed inside the Exocapsule®-SR, its potent lipid bilayer membrane kept intact until the moment of activation. Released into the Activator, the rose signal meets a Bio-Coenzyme Complex of NAD⁺ and Coenzyme A, a Multi-Peptide Complex and Expression-Line Peptides, a Ceramide Trio and a Nourishing Lipid Complex of squalane, shea and olive, leaving the skin plumped, cushioned and glazed with light, even over makeup.

Clinically Optimized To
  • Instantly cushion and plump the look of skin
  • Restore a dewy, glazed, hydrated finish
  • Visibly firm and smooth fine lines over time
  • Reinforce the moisture barrier
  • Refresh skin anytime, even over makeup
99.9% Pure Rosa Damascena Callus EVs TBA ppm Rose EV Concentration 48 mL Activator + Exocapsule®-SR

"Balance, restored in a single breath of mist."

Renewal · Glazing Mist

The Dual-Phase Architecture

Four bioactive functions · One mist

  • I

    Activate

    RDC-EV is lyophilized with trehalose and mannitol, its lipid bilayer membrane kept intact, and sealed inside the Exocapsule®-SR, then released into the Activator at the moment of use.

    Rosa Damascena Callus Extracellular Vesicles · Trehalose · Mannitol · Sodium Hyaluronate

  • II

    Energize

    Energizing coenzymes, vitamins and a six-amino-acid matrix revitalize the look of tired, stressed skin.

    Nicotinamide Adenine Dinucleotide · Coenzyme A · Biotin · Cyanocobalamin · Ascorbic Acid · Glutathione

  • III

    Cushion

    A skin-identical ceramide trio and nourishing plant lipids reinforce the moisture barrier without weight.

    Ceramide NP · Cholesterol · Phytosphingosine · Squalane · Shea Butter · Olive Fruit Oil

  • IV

    Firm

    A multi-peptide complex visibly firms and smooths, for skin that looks plumped and glazed.

    Copper Tripeptide-1 · Palmitoyl Pentapeptide-4 · Palmitoyl Tetrapeptide-7 · Acetyl Hexapeptide-8 · Palmitoyl Tripeptide-1

Exocapsule®-SR · RDC-EV, lyophilized and sealed until the moment of activation
The Patented Delivery System

RDC-EV — Rosa Damascena Callus Extracellular Vesicles

Purified to 99.9% through ExoCoBio's patented EXO-SCRT™ technology. The same science, the same purity standard and the same manufacturing discipline behind the in-clinic Exosome Regenerative Complex™ line.

Sealed until the moment of use. Activated for the moment it matters.

99.9%
Purity
78+
Patents
61+
Publications
2.3M+
Clinical Cases
Key Ingredients

Hero actives. Clinical architecture.

The Patented Delivery System

RDC-EV

Rosa Damascena Callus Extracellular Vesicles · TBA ppm · 99.9% pure.

Cellular Energy

Bio-Coenzyme Complex

NAD⁺ · Coenzyme A · Biotin · Vitamin B12 — energizes tired-looking skin.

Structural Lift

Multi-Peptide Complex

Copper Tripeptide-1 · Palmitoyl Pentapeptide-4 · Palmitoyl Tetrapeptide-7 · Palmitoyl Hexapeptide-12 — visibly firms and smooths.

Expression-Line Smoothing

Expression-Line Peptides

Acetyl Hexapeptide-8 · Dipeptide Diaminobutyroyl Benzylamide Diacetate · Pentapeptide-3 — softens the look of expression lines.

Barrier Reinforcement

Ceramide Trio

Ceramide NP · Cholesterol · Phytosphingosine — reinforces the moisture barrier.

Softness Without Weight

Nourishing Lipid Complex

Squalane · Shea Butter · Olive Fruit Oil — cushions without weight.

Supporting Cast

  • Amino Acid Matrix — (Tryptophan, Histidine, Lysine, Glutamic Acid, Serine, Methionine) supplies the building blocks of healthy-looking skin.
  • Niacinamide & Glutathione — refine the look of uneven tone.
  • Sodium Hyaluronate, Trehalose & Betaine — hold lasting hydration.
  • Coccinia Indica, Eclipta Prostrata & Cocoa — botanical conditioning.
Clinical Results

Proven outcomes. ExoCoBio science.

96%

Immediately Plumps and Cushions*

98%

Skin Looks Dewier and More Hydrated*

96%

Wears Beautifully Under and Over Makeup*

*In a consumer study of 30 subjects. Individual results may vary.

The Ritual

Morning, evening, and anytime.

  1. Insert the Exocapsule®-SR (Step 1) into the Activator (Step 2).

  2. Shake well until fully mixed.

  3. Mist evenly over the face from a suitable distance.

  4. Pat gently to absorb.

Use morning and evening, after the Refining Toning Essence, and throughout the day, over makeup, whenever skin needs a reset.

Cautions

For external use only, not to be swallowed. In case of accidental ingestion, seek professional assistance. Avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water. Stop using and consult a doctor if rash or irritation develops or persists. Keep out of reach of children.

This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and increase the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards.

Full Ingredients+

Exocapsule®-SR Rosa Damascena Callus Extracellular Vesicles, Sodium Hyaluronate, Mannitol, Trehalose, Potassium Chloride, Magnesium Sulfate, Tryptophan, Histidine, Lysine, Glutamic Acid, Serine, Methionine, Nicotinamide Adenine Dinucleotide, Biotin, Coenzyme A, Cyanocobalamin, Ascorbic Acid, Glutathione, Acetyl Hexapeptide-8, Nonapeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Disodium Palmitoyl Ethylhydroxyethylmonium Methosulfate, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, sh-Polypeptide-3, sh-Polypeptide-76, sh-Oligopeptide-1

Activator Water, Butylene Glycol, Niacinamide, Propanediol, 1,2-Hexanediol, Glycerin, Olea Europaea (Olive) Fruit Oil, Butyrospermum Parkii (Shea) Butter, Caprylic/Capric Triglyceride, Hydrogenated Lecithin, Squalane, Betaine, Polyglyceryl 10 Laurate, Fragrance, Polyglyceryl-4 Laurate, Disodium EDTA, Caprylyl Glycol, Ethylhexylglycerin, Adenosine, Caprylyl/Capryl Glucoside, Ceramide NP, Cholesterol, Coccinia Indica Fruit Extract, Eclipta Prostrata Extract, Phytosphingosine, Theobroma Cacao (Cocoa) Fruit Powder, Sodium Chloride, Sodium Citrate, Palmitoyl Hexapeptide-12, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Pentapeptide-3, Hexapeptide-9, Nonapeptide-1, Copper Tripeptide-1, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetyl Hexapeptide-8, Citric Acid, Tripeptide-1, Disodium Phosphate, Sodium Phosphate, sr-(Oligopeptide-91 Clostridium Botulinum Polypeptide-1)

Be among the first
to experience the difference.

The Biosignal Collection · The Advanced Treatment

Biosignal

Revitalizing Concentrate

The advanced high-concentration treatment

A high-concentration treatment powered by patented RDC-EV and engineered to do two things at the highest level at once: revitalize the look of tired, stressed skin and visibly smooth the signs of time. Built not on water but on pure Rosa Damascena Flower Water, each press of the precision pump releases a precisely dosed payload of the rose signal with a Smoothing Complex of adenosine, niacinamide and vitamin B12, a Hydration Complex and a Comfort Complex of panthenol, sealed in place by a Dual-Phase Emollient Cushion, refining the skin's surface to a smoother, more even, revitalized complexion.

Clinically Optimized To
  • Visibly smooth the look of fine lines and wrinkles
  • Refine texture and even the look of tone
  • Replenish and hold lasting moisture
  • Revitalize the look of tired, stressed skin
99.9% Pure Rosa Damascena Callus EVs TBA ppm Rose EV Concentration 21 mL Fill

"Not all skin concerns are everywhere. Some need to be addressed exactly where they are."

Biosignal · Revitalizing Concentrate

The R⁵ Architecture

Five forces · One system

  • R¹

    Rose

    The foundational vesicle intelligence, in a base of pure rose water.

    Rosa Damascena Callus Extracellular Vesicles · Rosa Damascena Flower Water

  • R²

    Restore

    Barrier-comforting humectants replenish and hold moisture.

    Panthenol · Sodium Hyaluronate · Glycerin · Polyglycerin-3

  • R³

    Resilience

    Visibly smooths and supports a firmer-looking surface.

    Adenosine · Hydroxyacetophenone

  • R⁴

    Replenish

    A dual-phase emollient cushion seals the treatment for a plumped, supple finish.

    Decyl Oleate · Isopropyl Myristate · Pentaerythrityl Tetraisostearate · Magnesium Sulfate

  • R⁵

    Radiance

    Refines the look of uneven tone and texture for a luminous finish.

    Niacinamide · Cyanocobalamin

The Patented Delivery System

RDC-EV — Rosa Damascena Callus Extracellular Vesicles

Purified to 99.9% through ExoCoBio's patented EXO-SCRT™ technology. The same science, the same purity standard and the same manufacturing discipline behind the in-clinic Exosome Regenerative Complex™ line.

Not a single-ingredient serum. A complete revitalizing system: concentration as ritual.

99.9%
Purity
78+
Patents
61+
Publications
2.3M+
Clinical Cases
Key Ingredients

Hero actives. Clinical architecture.

The Patented Delivery System

RDC-EV

Rosa Damascena Callus Extracellular Vesicles · TBA ppm · 99.9% pure.

The Rose Foundation

Rosa Damascena Flower Water

Rosa Damascena Flower Water — a pure rose-water foundation.

Visible Smoothing & Even Tone

Smoothing Complex

Adenosine · Niacinamide · Cyanocobalamin — visibly smooths and refines.

Deep Hydration

Hydration Complex

Sodium Hyaluronate · Glycerin · Polyglycerin-3 — replenishes and holds moisture.

Calm & Comfort

Comfort Complex

Panthenol · Hydroxyacetophenone — calms and comforts.

The Dual-Phase Seal

Dual-Phase Emollient Cushion

Decyl Oleate · Isopropyl Myristate · Pentaerythrityl Tetraisostearate — seals in moisture for a plumped finish.

Supporting Cast

  • Magnesium Sulfate — stabilizes the formula's dual-phase texture.
  • Propylene Glycol Dibenzoate — lends a silken, weightless glide.
Clinical Results

Proven outcomes. ExoCoBio science.

98%

Improvement in the Look of Fine Lines

83%

Reported Smoother Texture

92%

Improved Tonal Evenness

Based on a customer study · n=168 subjects · 8 weeks · twice-daily application · 2026. Individual results may vary.

The Ritual

Morning and evening. Precisely dosed.

  1. On first use, pump several times until the product dispenses.

  2. Pump an appropriate amount onto the required area.

  3. Gently spread over the entire face.

  4. Blend until fully absorbed.

Use morning and evening · after the mist, before serum.

Cautions

For external use only, not to be swallowed. In case of accidental ingestion, seek professional assistance. Avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water. Stop using and consult a doctor if rash or irritation develops or persists. Keep out of reach of children.

This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and increase the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards.

Full Ingredients+

Rosa Damascena Flower Water, Rosa Damascena Callus Extracellular Vesicles, Decyl Oleate, Glycerin, Isopropyl Myristate, Polyglycerin-3, Polyglyceryl-2 Dipolyhydroxystearate, Pentaerythrityl Tetraisostearate, Niacinamide, Propylene Glycol Dibenzoate, 1,2-Hexanediol, Polyglyceryl-3 Diisostearate, Magnesium Sulfate, Hydroxyacetophenone, Butylene Glycol, Ethylhexylglycerin, Maltodextrin, Fragrance, Adenosine, Sodium Citrate, Sodium Hyaluronate, Panthenol, Citric Acid, Cyanocobalamin

Be among the first
to experience the difference.

The Biosignal Collection · The Advanced Treatment

Intensive

Eye Concentrate

Advanced professional orbital treatment

A multi-zone orbital treatment powered by patented RDC-EV and engineered to do two things at the highest level at once: visibly depuff and brighten, while firming and smoothing the eye contour. Delivered through a cooling metal roller-ball that massages as it applies, each glide releases a DNA Fraction · Peptide Complex for structural lift, a Caffeine · Coffee Complex to depuff, a Brightening Complex of niacinamide, vitamin C and Kojyl Carboxy Dipeptide-23, Ceramide NP to reinforce the thinnest barrier on the face, and a Multi-Hyaluronic Complex of ten hyaluronic forms, for an eye contour that looks smoother, brighter and rested.

Clinically Optimized To
  • Visibly reduce the look of puffiness
  • Brighten the look of dark circles
  • Firm and smooth the orbital contour
  • Hydrate and reinforce the delicate eye-area barrier
99.9% Pure Rosa Damascena Callus EVs TBA ppm Rose EV Concentration 21 g Fill

"The most delicate skin on the face deserves the most intensive care."

Intensive · Eye Concentrate

The Orbital Architecture

Four bioactive zones · One system

  • I

    Firmness

    A plant-derived structural protein, Sodium DNA and a five-peptide complex visibly support and lift.

    Hydrolyzed Extensin · Sodium DNA · Copper Tripeptide-1 · Palmitoyl Pentapeptide-4 · Palmitoyl Tetrapeptide-7 · Palmitoyl Tripeptide-1 · Acetyl Hexapeptide-8

  • II

    Radiance

    Caffeine, coffee seed extract and a brightening trio depuff and brighten the look of the under eye.

    Caffeine · Coffea Arabica Seed Extract · Niacinamide · Ascorbic Acid · Kojyl Carboxy Dipeptide-23 · Adenosine

  • III

    Comfort

    Ceramide NP and madecassoside reinforce and calm the exceptionally thin barrier of the eye contour.

    Ceramide NP · Madecassoside · Panthenol

  • IV

    Hydration

    Ten forms of hyaluronic acid hydrate at multiple levels for a smooth, resilient finish.

    Ten-Form Hyaluronic Complex · Glycosyl Trehalose · Rosa Damascena Flower Water

The Patented Delivery System

RDC-EV — Rosa Damascena Callus Extracellular Vesicles

Purified to 99.9% through ExoCoBio's patented EXO-SCRT™ technology. The same science, the same purity standard and the same manufacturing discipline behind the in-clinic Exosome Regenerative Complex™ line.

Precision care for the orbital contour, morning and evening.

99.9%
Purity
78+
Patents
61+
Publications
2.3M+
Clinical Cases
Key Ingredients

Hero actives. Clinical architecture.

The Patented Delivery System

RDC-EV

Rosa Damascena Callus Extracellular Vesicles · TBA ppm · 99.9% pure.

Structural Lift

DNA Fraction · Peptide Complex

Hydrolyzed Extensin · Sodium DNA · GHK-Cu · Palmitoyl Pentapeptide-4 — structural lift, visibly firmer contour.

Depuffing · Microcirculation

Caffeine · Coffee Complex

Caffeine · Coffea Arabica Seed Extract · Adenosine — depuffs, restores microcirculation.

Barrier Reinforcement

Ceramide NP

Ceramide NP · Madecassoside · Panthenol — reinforces the thinnest barrier on the face.

Luminosity & Even Tone

Brightening Complex

Niacinamide · Ascorbic Acid · Kojyl Carboxy Dipeptide-23 — evens tone, restores luminosity.

Multi-Level Hydration

Multi-Hyaluronic Complex

Hyaluronic Acid · Sodium Hyaluronate · Hydrolyzed Hyaluronic Acid · Potassium Hyaluronate — ten forms, multi-level hydration.

Supporting Cast

  • Glycosyl Trehalose — locks in moisture.
  • Acetyl Hexapeptide-8 & Palmitoyl Tripeptide-1 — soften the look of expression lines.
  • Vitamin B12 — revitalizes the look of tired skin.
  • Rosa Damascena Flower Water — hydrates and grounds the formulation in its botanical origin.
Clinical Results

Proven outcomes. ExoCoBio science.

87%

Reduced Look of Puffiness

98%

Brighter Under-Eye Appearance

91%

Smoother Orbital Contour

Based on a customer study · n=123 subjects · 8 weeks · twice-daily application · 2026. Individual results may vary.

The Ritual

Morning and evening. Every zone.

  1. Dispense a small amount using the metal roller-ball applicator.

  2. Glide gently around the orbital bone, from the inner corner outward.

  3. Press lightly and roll to enhance absorption and deliver a cooling massage.

  4. Pat any remaining product softly with the ring finger.

Use morning and evening, after serum and before cream.

Cautions

For external use only. Keep out of reach of children. Stop using and consult a doctor if rash or irritation develops or persists.

This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and increase the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards.

Full Ingredients+

Water, Rosa Damascena Callus Extracellular Vesicles, Glycerin, Caprylic/Capric Triglyceride, Hydrogenated Poly (C6-14 Olefin), Polyglyceryl-3 Methylglucose Distearate, Niacinamide, Pentaerythrityl Tetraethylhexanoate, Pentaerythrityl Tetraisostearate, Dimethicone, Cetearyl Alcohol, Glycosyl Trehalose, Glyceryl Stearate, C14-22 Alcohols, Hydrogenated Starch Hydrolysate, Polyglyceryl-10 Laurate, Hydroxyacetophenone, Butylene Glycol, Rosa Damascena Flower Water, 1,2-Hexanediol, C12-20 Alkyl Glucoside, Ammonium Acryloyldimethyltaurate/VP Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Ethylhexylglycerin, Panthenol, Xanthan Gum, Maltodextrin, Sodium Stearoyl Glutamate, Adenosine, Sodium Citrate, Disodium EDTA, Glyceryl Acrylate/Acrylic Acid Copolymer, Sodium Hyaluronate, Hydrolyzed Extensin, Coffea Arabica (Coffee) Seed Extract, Caffeine, Ceramide NP, Sodium DNA, Citric Acid, Ascorbic Acid, Madecassoside, Cyanocobalamin, Kojyl Carboxy Dipeptide-23, Copper Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Dimethylsilanol Hyaluronate, Hyaluronic Acid, Potassium Hyaluronate, Sodium Hyaluronate Crosspolymer, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Dimethylsilanol, Sodium Acetylated Hyaluronate

Be among the first
to experience the difference.

The Luminous Collection · The Glow Ritual

Refining

Toning Essence

The first step to clarity

A clarifying essence powered by patented RDC-EV and engineered to do two things at once: refine the skin's surface and prepare it for every step that follows. Built on pure Rosa Damascena Flower Water, it pairs the rose signal with a Gentle Resurfacing Trio of willow bark water with glycolic, lactic and salicylic acids, a Tone-Correcting Complex of tranexamic acid, niacinamide and glutathione, a Five-Ceramide Complex, an Alpine Botanical Complex of edelweiss callus, chamomile and centella, and a Vitamin Complex of C, B5, B6 and B12, revealing skin that looks clearer, smoother and more even.

Clinically Optimized To
  • Refine the look of pores and surface texture
  • Begin to visibly even skin tone
  • Calm and comfort the barrier
  • Prepare skin to receive every step that follows
99.9% Pure Rosa Damascena Callus EVs TBA ppm Rose EV Concentration 150 mL Fill

"Every luminous complexion begins with a clear canvas."

Refining · Toning Essence

The Clarity Architecture

Four luminous zones · One system

  • I

    Refine

    Willow bark water and a gentle AHA/BHA trio smooth the surface and refine the look of pores.

    Salix Alba (Willow) Bark Water · Glycolic Acid · Lactic Acid · Salicylic Acid

  • II

    Even

    A tone-correcting complex begins to visibly even the complexion.

    Tranexamic Acid · Niacinamide · Glutathione · Sodium Ascorbyl Phosphate

  • III

    Comfort

    A five-ceramide complex and soothing botanicals keep skin balanced.

    Ceramide NP · NS · AS · AP · EOP · Panthenol · Centella Asiatica · Chamomile

  • IV

    Hydrate

    A rose-water base with betaine and hyaluronate prepares skin to receive every step that follows.

    Rosa Damascena Flower Water · Betaine · Sodium Hyaluronate · Glycerin

The Patented Delivery System

RDC-EV — Rosa Damascena Callus Extracellular Vesicles

Purified to 99.9% through ExoCoBio's patented EXO-SCRT™ technology. The same science, the same purity standard and the same manufacturing discipline behind the in-clinic Exosome Regenerative Complex™ line.

Refine. Prepare. Reveal.

99.9%
Purity
78+
Patents
61+
Publications
2.3M+
Clinical Cases
Key Ingredients

Hero actives. Clinical architecture.

The Patented Delivery System

RDC-EV

Rosa Damascena Callus Extracellular Vesicles · TBA ppm · 99.9% pure.

Polish & Refine

Gentle Resurfacing Trio

Salix Alba Bark Water · Glycolic Acid · Lactic Acid · Salicylic Acid — refines the look of pores and texture.

Luminosity & Even Tone

Tone-Correcting Complex

Tranexamic Acid · Niacinamide · Glutathione — visibly evens tone.

Barrier Reinforcement

Five-Ceramide Complex

Ceramide NP · Ceramide NS · Ceramide AS · Ceramide AP · Ceramide EOP — comforts and reinforces the barrier.

Soothe & Protect

Alpine Botanical Complex

Leontopodium Alpinum Callus Culture · Chamomilla Recutita · Centella Asiatica — soothes and protects.

Revitalize

Vitamin Complex

Sodium Ascorbyl Phosphate · Pyridoxine HCl · Cyanocobalamin · Calcium Pantothenate — revitalizes and brightens.

Supporting Cast

  • Adenosine — visibly smooths.
  • Betaine & Panthenol — hydrate and condition.
  • Phellinus Linteus, Burdock Root & Vitex — botanical conditioning.
  • Adansonia (Baobab) Seed Oil — nourishes.
  • Synthetic Fluorphlogopite — lends a subtle luminous finish.
The Ritual

The first step. Every ritual.

  1. After cleansing, dispense an appropriate amount into the palms.

  2. Softly press into the skin to enhance absorption.

  3. Follow with the Renewal Glazing Mist.

Use morning and evening. Always follow with sunscreen in the morning.

Cautions

For external use only, not to be swallowed. In case of accidental ingestion, seek professional assistance. Avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water. Stop using and consult a doctor if rash or irritation develops or persists. Keep out of reach of children.

This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and increase the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards.

Full Ingredients+

Rosa Damascena Flower Water, Rosa Damascena Callus Extracellular Vesicles, Salix Alba (Willow) Bark Water, Niacinamide, 1,2-Hexanediol, Glycerin, Water, Betaine, Butylene Glycol, Isopentyldiol, Octyldodeceth-16, Panthenol, Mannitol, Microcrystalline Cellulose, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Tranexamic Acid, Xanthan Gum, Zea Mays (Corn) Starch, Maltodextrin, Ethylhexylglycerin, Fragrance, Cellulose Gum, Adenosine, Synthetic Fluorphlogopite, Sodium Citrate, Sodium Phytate, Centella Asiatica Extract, Sodium Hyaluronate, Glutathione, Tocopheryl Acetate, Phellinus Linteus Extract, Arctium Lappa Root Extract, Hydrogenated Lecithin, Portulaca Oleracea Extract, Leontopodium Alpinum Callus Culture Extract, Chamomilla Recutita (Matricaria) Flower Extract, Vitex Agnus-Castus Extract, Red 30 (CI 73360), Calcium Pantothenate, Sodium Starch Octenylsuccinate, Citric Acid, Sodium Ascorbyl Phosphate, Pyridoxine HCl, Caprylic/Capric Triglyceride, Cyanocobalamin, Adansonia Digitata Seed Oil, Ceramide NP, Ceramide NS, Ceramide AS, Lactic Acid, Ceramide AP, Ceramide EOP, Glycolic Acid, Salicylic Acid

Be among the first
to experience the difference.

The Luminous Collection · The Glow Ritual

Luminous

Perfecting Serum

A tone-perfecting luminous serum

A tone-perfecting serum powered by patented RDC-EV and engineered to do two things at the highest level at once: visibly even skin tone and bring clarity to the complexion. Built on pure Rosa Damascena Flower Water and dispensed through a precision press-button applicator, each application delivers a Brightening Complex of niacinamide, arbutin, glutathione and vitamin C, Collagen and Polyglutamic Acid to plump and smooth, a Five-Ceramide Complex, calming Bisabolol and Chamomile, and Edelweiss Callus Culture, for a complexion that looks perfected and lit from within.

Clinically Optimized To
  • Visibly even tone and soften the look of dark spots
  • Bring clarity and luminosity to the complexion
  • Plump and smooth the surface
  • Reinforce and calm the barrier
99.9% Pure Rosa Damascena Callus EVs TBA ppm Rose EV Concentration 30 mL Fill

"Perfection is not a finish. It is clarity, revealed."

Luminous · Perfecting Serum

The Luminous Architecture

Four luminous zones · One system

  • I

    Clarify

    A four-part brightening complex visibly evens tone and softens the look of dark spots.

    Niacinamide · Arbutin · Glutathione · Sodium Ascorbyl Phosphate

  • II

    Plump

    Collagen and polyglutamic acid hydrate and smooth for a refined, supple surface.

    Collagen · Polyglutamic Acid · Sodium Hyaluronate · Glycereth-26

  • III

    Comfort

    A five-ceramide complex and calming botanicals keep skin balanced.

    Ceramide NP · NS · AS · AP · EOP · Bisabolol · Chamomile · Centella Asiatica

  • IV

    Nourish

    Antioxidant vitamins and botanical oils protect the look of radiant skin.

    Leontopodium Alpinum Callus Culture · Tocopheryl Acetate · Adansonia Digitata Seed Oil

The Patented Delivery System

RDC-EV — Rosa Damascena Callus Extracellular Vesicles

Purified to 99.9% through ExoCoBio's patented EXO-SCRT™ technology. The same science, the same purity standard and the same manufacturing discipline behind the in-clinic Exosome Regenerative Complex™ line.

Clarity, illuminated.

99.9%
Purity
78+
Patents
61+
Publications
2.3M+
Clinical Cases
Key Ingredients

Hero actives. Clinical architecture.

The Patented Delivery System

RDC-EV

Rosa Damascena Callus Extracellular Vesicles · TBA ppm · 99.9% pure.

Luminosity & Even Tone

Brightening Complex

Niacinamide · Arbutin · Glutathione · Sodium Ascorbyl Phosphate — evens tone, restores luminosity.

Plump & Smooth

Collagen · Polyglutamic Acid

Collagen · Polyglutamic Acid · Sodium Hyaluronate — plumps and smooths.

Barrier Reinforcement

Five-Ceramide Complex

Ceramide NP · Ceramide NS · Ceramide AS · Ceramide AP · Ceramide EOP — reinforces the barrier.

Calm & Comfort

Bisabolol · Chamomile

Bisabolol · Chamomilla Recutita Flower Extract · Centella Asiatica Extract — calms and comforts.

Alpine Protection

Edelweiss Callus Culture

Leontopodium Alpinum Callus Culture Extract · Portulaca Oleracea Extract — alpine botanical protection.

Supporting Cast

  • Adenosine — visibly smooths.
  • Vitamins B5, B6 & B12 — revitalize.
  • Burdock Root, Phellinus Linteus & Vitex — botanical conditioning.
  • Baobab Seed & Palm Kernel Oils — nourish.
  • Synthetic Fluorphlogopite — lends an instant luminous finish.
The Ritual

Morning and evening. Clarity, revealed.

  1. Press the button at the base to dispense an appropriate amount onto the desired area.

  2. Gently spread until fully absorbed.

  3. Follow with the Intensive Eye Concentrate and Radiance Corrective Cream.

Use morning and evening, after the Biosignal Revitalizing Concentrate. Always follow with sunscreen in the morning.

Cautions

For external use only, not to be swallowed. In case of accidental ingestion, seek professional assistance. Avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water. Stop using and consult a doctor if rash or irritation develops or persists. Keep out of reach of children.

This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and increase the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards.

Full Ingredients+

Rosa Damascena Flower Water, Rosa Damascena Callus Extracellular Vesicles, Butylene Glycol, Niacinamide, Dipropylene Glycol, 1,2-Hexanediol, Glycerin, Water, Octyldodeceth-16, Glycereth-26, Mannitol, Tromethamine, Silica, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Microcrystalline Cellulose, Elaeis Guineensis (Palm) Oil, Ethylhexylglycerin, Maltodextrin, Zea Mays (Corn) Starch, Fragrance, Adenosine, Synthetic Fluorphlogopite, Sodium Citrate, Sodium Phytate, Xanthan Gum, Cellulose Gum, Sodium Hyaluronate, Elaeis Guineensis (Palm) Kernel Oil, Tocopheryl Acetate, Centella Asiatica Extract, Arctium Lappa Root Extract, Phellinus Linteus Extract, Hydrogenated Lecithin, Portulaca Oleracea Extract, Vitex Agnus-Castus Extract, Leontopodium Alpinum Callus Culture Extract, Chamomilla Recutita (Matricaria) Flower Extract, Red 30 (CI 73360), Collagen, Arbutin, Calcium Pantothenate, Citric Acid, Sodium Starch Octenylsuccinate, Sodium Ascorbyl Phosphate, Pyridoxine HCl, Bisabolol, Glutathione, Caprylic/Capric Triglyceride, Cyanocobalamin, Adansonia Digitata Seed Oil, Ceramide NP, Polyglutamic Acid, Ceramide NS, Ceramide AS, Ceramide AP, Ceramide EOP

Be among the first
to experience the difference.

The Luminous Collection · The Glow Ritual

Radiance

Corrective Cream

The final luminous veil

A corrective cream powered by patented RDC-EV and engineered to do two things at once: correct the look of uneven tone over time and illuminate the skin the moment it is applied. The rose signal is paired with a Tone-Correcting Complex of tranexamic acid, niacinamide and glutathione, Light-Reflecting Minerals, a Vitamin Complex of C, B6, B12 and E, a Moisture Complex of glyceryl glucoside and hyaluronic acid, and Comfort Lipids. Its rich yet weightless texture seals in every step of the ritual, leaving the skin comforted, nourished and quietly radiant.

Clinically Optimized To
  • Visibly correct uneven tone over time
  • Give an immediate, luminous finish
  • Lock in lasting hydration
  • Nourish and protect the look of radiant skin
99.9% Pure Rosa Damascena Callus EVs TBA ppm Rose EV Concentration 50 mL Fill

"Radiance is not applied. It is revealed."

Radiance · Corrective Cream

The Radiance Architecture

Four luminous zones · One system

  • I

    Correct

    A tone-correcting trio visibly evens the complexion over time.

    Tranexamic Acid · Niacinamide · Glutathione

  • II

    Illuminate

    Light-reflecting minerals give an immediate, luminous finish.

    Synthetic Fluorphlogopite · Rosa Damascena Flower Water

  • III

    Nourish

    A vitamin complex revitalizes and protects the look of radiant skin.

    Sodium Ascorbyl Phosphate · Pyridoxine HCl · Cyanocobalamin · Calcium Pantothenate · Tocopheryl Acetate

  • IV

    Seal

    Moisture-binding glucosides and nourishing emollients lock in every step of the ritual.

    Glyceryl Glucoside · Sodium Hyaluronate · Caprylic/Capric Triglyceride · Cetyl Ethylhexanoate · Arginine

The Patented Delivery System

RDC-EV — Rosa Damascena Callus Extracellular Vesicles

Purified to 99.9% through ExoCoBio's patented EXO-SCRT™ technology. The same science, the same purity standard and the same manufacturing discipline behind the in-clinic Exosome Regenerative Complex™ line.

Correct. Illuminate. Seal.

99.9%
Purity
78+
Patents
61+
Publications
2.3M+
Clinical Cases
Key Ingredients

Hero actives. Clinical architecture.

The Patented Delivery System

RDC-EV

Rosa Damascena Callus Extracellular Vesicles · TBA ppm · 99.9% pure.

Tone Correction

Tone-Correcting Complex

Tranexamic Acid · Niacinamide · Glutathione — visibly corrects uneven tone.

Instant Luminosity

Light-Reflecting Minerals

Synthetic Fluorphlogopite — an immediate luminous finish.

Revitalize & Protect

Vitamin Complex

Sodium Ascorbyl Phosphate · Pyridoxine HCl · Cyanocobalamin · Tocopheryl Acetate — revitalizes and protects.

Lasting Hydration

Moisture Complex

Glyceryl Glucoside · Sodium Hyaluronate · Glycerin — lasting, cushioned hydration.

The Final Seal

Comfort Lipids

Caprylic/Capric Triglyceride · Cetyl Ethylhexanoate · Hydrogenated Lecithin — comforts and seals in moisture.

Supporting Cast

  • Arginine — supports the skin's natural moisture balance.
  • Hydroxyacetophenone — soothes.
  • Calcium Pantothenate — conditions.
  • Rosa Damascena Flower Water — hydrates and grounds the formulation in its botanical origin.
The Ritual

The final step. Morning and evening.

  1. Using the enclosed spatula, take an appropriate amount.

  2. Apply evenly over the entire face.

  3. Gently press until fully absorbed.

Use as the final step, morning and evening. Follow with a broad-spectrum sunscreen in the morning.

Cautions

For external use only, not to be swallowed. In case of accidental ingestion, seek professional assistance. Avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water. Stop using and consult a doctor if rash or irritation develops or persists. Keep out of reach of children.

This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and increase the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards.

Full Ingredients+

Water, Rosa Damascena Callus Extracellular Vesicles, Glycerin, Caprylic/Capric Triglyceride, Niacinamide, Butylene Glycol, Cetyl Ethylhexanoate, Tranexamic Acid, Cetearyl Alcohol, Propanediol, Polyglyceryl-3 Distearate, Dimethicone, 1,2-Hexanediol, Pentaerythrityl Tetraethylhexanoate, Glyceryl Glucoside, Glyceryl Stearate, Rosa Damascena Flower Water, Mannitol, Ammonium Acryloyldimethyltaurate/VP Copolymer, Hydroxyacetophenone, Palmitic Acid, Arginine, Carbomer, Stearic Acid, Microcrystalline Cellulose, Glutathione, Glyceryl Stearate Citrate, Maltodextrin, Ethylhexylglycerin, Zea Mays (Corn) Starch, Synthetic Fluorphlogopite, Sodium Citrate, Disodium EDTA, Sodium Hyaluronate, Tocopheryl Acetate, Hydrogenated Lecithin, Red 30 (CI 73360), Citric Acid, Calcium Pantothenate, Sodium Starch Octenylsuccinate, Sodium Ascorbyl Phosphate, Pyridoxine HCl, Cyanocobalamin

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to experience the difference.

The Luminous Collection · The Glow Ritual

PhotoDefense

SPF 50+ PA++++

The final luminous shield

Available in select international markets · Not sold in the U.S.

The final step of the Glow Ritual, and the one that protects every step before it. PhotoDefense pairs very high SPF 50+ PA++++ protection with patented RDC-EV, engineered to do two things at once: shield the skin from UVA and UVB exposure and keep it looking clear, even and radiant. An advanced four-filter UV Defense Complex is joined by a Tone-Perfecting Complex of tranexamic acid, niacinamide and glutathione, a Smoothing & Vitamin Complex of adenosine, vitamin B12 and vitamin E, and a Rose Hydration Complex of Rosa Damascena Flower Water and hyaluronic acid. Its weightless, soft-focus texture finishes the ritual without weight, so the radiance you build is the radiance you keep.

Clinically Optimized To
  • Protect skin from UVA and UVB exposure with SPF 50+ PA++++
  • Maintain the look of clear, even, radiant skin
  • Help protect the look of in-clinic results every day
  • Hydrate with a weightless, soft-focus finish
99.9% Pure Rosa Damascena Callus EVs TBA ppm Rose EV Concentration

"The final step protects every step before it."

PhotoDefense · SPF 50+ PA++++

The PhotoDefense Architecture

Four protective zones · One veil

  • I

    Shield

    An advanced four-filter system delivers very high SPF 50+ PA++++ protection across UVB and UVA.

    Ethylhexyl Triazone · Diethylamino Hydroxybenzoic Hexyl Benzoate · Drometrizole Trisiloxane · Methylene Bis-Benzotriazolyl Tetramethylbutylphenol

  • II

    Perfect

    A tone-perfecting trio keeps the complexion looking clear and even.

    Tranexamic Acid · Niacinamide · Glutathione

  • III

    Restore

    Adenosine and vitamins B12 and E revitalize and protect the look of radiant skin.

    Adenosine · Cyanocobalamin · Tocopherol

  • IV

    Veil

    Rose water, hyaluronic acid and a soft-focus silica finish leave skin hydrated and refined, never heavy.

    Rosa Damascena Flower Water · Sodium Hyaluronate · Sphingomonas Ferment Extract · Glycerin · Silica

The Patented Delivery System

RDC-EV — Rosa Damascena Callus Extracellular Vesicles

Purified to 99.9% through ExoCoBio's patented EXO-SCRT™ technology. The same science, the same purity standard and the same manufacturing discipline behind the in-clinic Exosome Regenerative Complex™ line.

Shield. Perfect. Preserve.

99.9%
Purity
78+
Patents
61+
Publications
2.3M+
Clinical Cases
Key Ingredients

Hero actives. Clinical architecture.

The Patented Delivery System

RDC-EV

Rosa Damascena Callus Extracellular Vesicles · TBA ppm · 99.9% pure.

UVA · UVB Protection

UV Defense Complex

Ethylhexyl Triazone · Diethylamino Hydroxybenzoic Hexyl Benzoate · Drometrizole Trisiloxane · Methylene Bis-Benzotriazolyl Tetramethylbutylphenol — very high SPF 50+ PA++++ protection from UVA and UVB.

Clear, Even Tone

Tone-Perfecting Complex

Tranexamic Acid · Niacinamide · Glutathione — keeps the look of tone clear and even.

Revitalize & Protect

Smoothing & Vitamin Complex

Adenosine · Cyanocobalamin · Tocopherol — revitalizes and protects the look of radiant skin.

Lasting Hydration

Rose Hydration Complex

Rosa Damascena Flower Water · Sodium Hyaluronate · Sphingomonas Ferment Extract · Glycerin — weightless, lasting hydration.

The Final Veil

Soft-Focus Finish

Silica · Butyloctyl Salicylate · Coco-Caprylate/Caprate · Caprylyl Methicone — a silky, weightless veil.

Supporting Cast

  • Butyloctyl Salicylate — helps the filters spread evenly.
  • Dimethicone/Vinyl Dimethicone Crosspolymer — lends a velvety, weightless feel.
  • Behenyl Alcohol & Sodium Stearoyl Glutamate — keep the texture stable and comfortable.
  • Ethylhexylglycerin — conditions.
The Ritual

Every morning. The final step.

  1. Apply an adequate amount evenly to the face and other areas exposed to the sun.

  2. Use as the final step of the morning ritual.

  3. Reapply as needed, especially after sweating or prolonged sun exposure.

Use every morning as the final step, after the Radiance Corrective Cream.

Cautions

For external use only, not to be swallowed. In case of accidental ingestion, seek professional assistance. Avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water. Stop using and consult a doctor if rash or irritation develops or persists. Keep out of reach of children.

This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and increase the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards.

Full Ingredients+

Water, Rosa Damascena Callus Extracellular Vesicles, Niacinamide, Dibutyl Adipate, Propanediol, Ethylhexyl Triazone, Butyloctyl Salicylate, Diethylamino Hydroxybenzoic Hexyl Benzoate, Drometrizole Trisiloxane, Methylene Bis Benzotriazolyl Tetramethylbutylphenol, Coco-Caprylate/Caprate, Caprylyl Methicone, 1,2-Hexanediol, Butylene Glycol, Silica, Pentylene Glycol, Tranexamic Acid, Dimethicone/Vinyl Dimethicone Crosspolymer, Behenyl Alcohol, Poly C10-30 Alkyl Acrylate, Polyglyceryl-3 Methylglucose Distearate, Decyl Glucoside, Tromethamine, Rosa Damascena Flower Water, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Glutathione, Sodium Stearoyl Glutamate, Sphingomonas Ferment Extract, Ethylhexylglycerin, Adenosine, Maltodextrin, Glycerin, Sodium Citrate, Xanthan Gum, Sodium Hyaluronate, Cyanocobalamin, Tocopherol, Citric Acid

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to experience the difference.

Discover

Explore the World of BENEV

Education, protocols, and provider resources — everything you need to support ASCEplus Platinum™ in your practice.

These materials are intended for licensed BENEV providers. Contact your Account Manager for full access to downloadable files.

Order Forms

HCP

Healthcare Provider Order Form

Submit a wholesale product order request directly to your Account Manager.

Open Order Form →
Pt

Patient Order Form

Coming soon, alongside the Patient track.

Coming Soon

Practice Materials

Booklet

Poster

Brochure

Banner

Social Images

A scrolling preview of current product photography, pulled straight from the site.

Protocols

01

Standard Homecare Protocol

Complete Biosignal + Luminous daily regimen guide — morning/evening routines, product sequencing, and layering instructions.

Download PDF — Coming Soon
02

Post-Procedure Recovery Protocol

Accelerated recovery for patients following injectable, laser, or energy device treatments. RDC-EV homecare for weeks 1–4.

Download PDF — Coming Soon
03

Anti-Aging Maintenance Protocol

Long-term homecare for prevention and regenerative maintenance. 12-week program with quarterly reassessment checkpoints.

Download PDF — Coming Soon
04

Sensitive Skin Introduction Protocol

Gradual introduction for patients with reactive or compromised skin barriers. Modified product sequencing with tolerance-building phase.

Download PDF — Coming Soon

FAQ

Drafted patient-facing for now — likely worth a provider-specific pass once the Patient track is built.

RDC-EV stands for Rosa Damascena Callus Extracellular Vesicles: the nano-sized messengers cells use to communicate, isolated from cultivated Damask rose callus and purified to 99.9% through patented EXO-SCRT™ technology. Not an extract. Not a hydrosol. Not an oil. The rose's own signal.

ASCEplus PLATINUM is built on ExoCoBio's extracellular vesicle platform, backed by 61+ peer-reviewed publications. Its plant-derived vesicles are purified to 99.9%, skin-irritation tested and made in cGMP, ISO-certified facilities, and the line is available exclusively through licensed aesthetic providers.

Follow your provider's specific protocol. In general: cleanse, prepare with the Refining Toning Essence, then layer the Renewal Glazing Mist, Biosignal Revitalizing Concentrate, Luminous Perfecting Serum and Intensive Eye Concentrate, and seal with the Radiance Corrective Cream. Finish with sunscreen every morning. Always follow your provider's instructions over general guidance.

Some formulas give an immediate finish (the Renewal Glazing Mist cushions on contact; the Radiance Corrective Cream illuminates as it is applied), while tone and texture benefits build with consistent morning and evening use. Your provider will set expectations for your specific regimen. Individual results may vary.

ASCEplus PLATINUM™ is exclusively available through your authorized aesthetic provider. It is not sold through any retail channel or online marketplace. If you see it sold elsewhere, it may be counterfeit. Contact your provider directly to refill your regimen.

First Access

Join the Waitlist

Be among the first qualified practices to receive ASCEplus Platinum™.

Register to receive the complete product line information, provider pricing, and official drop date notification. First access is reserved for qualified aesthetic practices.

Press & PR

Apply for a PR Box

Request press access to ASCEplus Platinum™ before launch.

Tell us about your outlet, platform, or practice and we'll be in touch about press sampling ahead of the official drop date.

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